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Meeting Registration Grants You Access to ALL Zoom Sessions

Pathobiology for Investigators, Students, and Academicians
Young Investigators Virtual Meeting

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Tuesday   |   Wednesday   |   Thursday  

Tuesday, October 5, 2021
 

Welcome to the PISA 2021 Young Investigators Virtual Meeting
Patricia D’Amore, PhD, ASIP President
Schepens Eye Research Institute/Harvard Medical School

Alexander T. Sougiannis, PhD
SESSION 1 - Cancer Pathobiology and Neuropathology
Session Co-Chairs: Alexander T. Sougiannis, PhD • Michelle Alves, PhD
12:30 PM - 3:30 PM (EDT)
Michelle Alves, PhD

12:30 PM -
1:15 PM (EDT)

Isaiah J. Fidler

Isaiah J. Fidler Memorial Keynote Lecture

“The Metastatic Cell is a Decathlon Champion”

Diane R. Bielenberg, PhD • Boston Children's Hospital/Harvard Medical School

ABSTRACT
About the Keynote Speaker

Diane R. Bielenberg

Young Investigator Short Talks

  • 1:15 PM - 1:30 PM (EDT)
    CAN1 - DCLK1 Promotes Cisplatin Resistance in Ovarian Cancer

    Samrita Dogra1,2, Katherine Moxley2,3, and Bethany N. Hannafon1,2
    1Department of Obstetrics and Gynecology, 2Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 3Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI

Samita Dogra
  • 1:30 PM - 1:45 PM (EDT)
    CAN2 - Targeting the DNA Damage Response Pathway by Combination of ATR and PARP Inhibition Imparts Synthetic Lethality to Cervical Cancer Cells

    Marlee Hill1, Sugantha Priya Elayapillai2,3, Bethany N. Hannafon2,3, and Katherine Moxley2,4
    1College of Medicine, University of Oklahoma, Oklahoma City, OK, 2Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 3Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 4Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI

Marlee Hill
  • 1:45 PM - 2:00 PM (EDT)
    CAN3 - Collagen Hydroxyproline Analysis of Colon Cancer Polyps in Patients Within the Appalachian Mountain Region
    Alexander T. Sougiannis1, Gavin T. Cauley1, and Peggi M. Angel2
    1Medical University of South Carolina, College of Medicine, Charleston, SC, 2Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC
     
Alexander T. Sougiannis
  • 2:00 PM - 2:15 PM (EDT)
    CAN4 - CECR2 Drives Breast Cancer Metastasis by Suppressing Macrophage Inflammatory Responses
    Meiling Zhang and Qin Yan
    Department of Pathology, Yale School of Medicine, New Haven, CT
Meiling Zhang
  • 2:15 PM - 2:30 PM (EDT)
    NEURO1 - PECAM-1 Blockade Reduces Neutrophil Infiltration into the Subcortex Post-Stroke
    Erika Arias, Neil Avadhoot Nadkarni, Raymond S. Fang, Maureen Haynes, Ayush Batra, William A. Muller, and David P. Sullivan
    Department of Pathology, Northwestern University, Chicago, IL
     
Erika Arias
  • 2:30 PM - 2:45 PM (EDT)
    NEURO2 - AAV-Mediated Gene Replacement Therapy is Beneficial in Unverricht-Lundborg Disease Mouse Model
    Emrah Gumusgoz, Sahba Kasiri, Jun Wu, Matthew Dear, Xin Chen, and Berge Minassian
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX
     
Emrah Gumusgoz
  • 2:45 PM - 3:00 PM (EDT)
    NEURO3 - Neuronal Death and Inflammation in Brain of SARS-CoV-2 Infected Non-Human Primates
    Meredith G. Mayer2, Ibolya Rutkai1, Linh M. Hellmers2, Bo Ning3, Zhen Huang3, Christopher J. Monjure2, Carol Coyne2, Rachel Silvestri2, Nadia Golden2, Krystle Hensley2, Kristin Chandler2, Gabrielle Lehmicke2, Gregory J. Bix1, Nicholas J. Maness2, Kasi Russell-Lodrigue2, Tony Y. Hu3, Chad J. Roy2, Robert V. Blair2, Rudolf Bohm2, Lara A. Doyle-Meyers2, Jay Rappaport2, and Tracy Fischer2
    1Department of Neurosurgery, Clinical Neuroscience Research Center, Tulane University School of Medicine, New Orleans, LA’ 2Tulane National Primate Research Center, Covington, LA, 3Center for Cellular and Molecular Diagnostics, Tulane University School of Medicine, New Orleans, LA
     
Meredith G. Mayer
  • 3:00 PM - 3:15 PM (EDT)
    NEURO4 - Interactions Between Autophagy, Herpesvirus, and Neurodegeneration in Alzheimer’s Disease
    Amir Nafchi1, Mona Esmaeili1, Pouya Raeisinafchi2, Orrin Myers4, and Elaine Bearer3
    1Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, NM, 2Department of Psychology, Neuroscience & Behavior, McMaster University, Hamilton, ON, Canada, 3Department of Pathology, University of New Mexico School of Medicine, Albuquerque, NM, 4Department of Family and Community Medicine, University of New Mexico School of Medicine, Albuquerque, NM
     
Amir Nafchi
  • 3:15 PM - 3:30 PM (EDT)
    NEURO5 - Early Life Adversity Potentiates Adult Response to Acute Threat: A Brain-wide Neuroimaging and Behavior Study
    Taylor W. Uselman1, Russell E. Jacobs2, Elaine L. Bearer1,3
    1Department of Pathology, University of New Mexico Health Science Center, Albuquerque, NM, 2Zilkha Neurogenetic Institute, USC Keck School of Medicine, Los Angeles, CA, 3Biology and Biological Engineering, Caltech, Pasadena, CA
     
Taylor W. Uselman
3:30 PM -
4:00 PM (EDT)
COFFEE BREAK
Kristen Engevik, PhD
SESSION 2 - Pathobiology of Infectious Disease
Session Co-Chairs: Kristen Engevik, PhD • Francisco J. Carrillo-Salinas, PhD
4:00 PM - 6:00 PM (EDT)
Francisco J. Carrillo-Salinas, PhD

4:00 PM -
4:45 PM (EDT)

Emanuel Rubin

Emanuel Rubin Memorial Keynote Lecture

“Understanding HIV Infection in the Female Genital Tract”

Marta Rodriguez-Garcia, MD, PhD • Tufts University School of Medicine 

ABSTRACT
About the Keynote Speaker

Marta Rodriguez-Garcia

Young Investigator Short Talks

  • 4:45 PM - 5:00 PM (EDT)
    IND1 - Sofia SARS Antigen FIA and Reverse-Transcriptase Polymerase Chain Reaction: Comparing Diagnostic Methods

    Blaire Anderson1, Anna Bouck1, Michael Lambert2, Dorothy Martin1,2, Heather Steinmetz1, Samantha Allen1, Joel Lefferts1, and Bing Ren1,2
    1Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, 2Department of Pathology and Laboratory Medicine, Springfield Hospital, Springfield, VT

Blaire Anderson
  • 5:00 PM - 5:15 PM (EDT)
    IND2 - Estradiol Levels Influence Neutrophil Responses Against HIV in Women
    Anna Borchers1, Laura Moreno de Lara1,2, Ragav S Parthasarathy1,3, Christina Ochsenbauer4, Alexander Panda5,6, Francisco J. Carrillo-Salinas1, and Marta Rodriguez-Garcia1,3
    1Department of Immunology, Tufts University School of Medicine, Boston MA, 2Immunology Unit, Biomedical Research Centre, University of Granada, Granada, Spain, 3Immunology Program, Tufts Graduate School of Biomedical Sciences, Boston, MA, 4Department of Medicine and UAB Center for AIDS Research, University of Alabama, Birmingham, AL, 5Tufts Medical Center/Division of Pulmonary and Critical Care, Boston, MA, 6Tufts Clinical and Translational Science Institute, Boston, MA
     
Anna Borchers
  • 5:15 PM - 5:30 PM (EDT)
    IND3 - SCFAs Impact Neutrophil Response to HIV Infection
    Francisco J. Carrillo-Salinas1, Ragav S. Parthasarathy1,2, Laura Moreno de Lara1,3, Anna Borchers1, Christina Ochsenbauer4, Alexander Panda5,6, and Marta Rodriguez-Garcia1,2
    1Department of Immunology, Tufts University School of Medicine, Boston, MA, 2Immunology Program, Tufts Graduate School of Biomedical Sciences, Boston, MA, 3Immunology Unit, Biomedical Research Centre, University of Granada, Granada, Spain, 4Department of Medicine and UAB Center for AIDS Research, University of Alabama, Birmingham, AL, 5Tufts Medical Center/Division of Pulmonary and Critical Care, Boston, MA, 6Tufts Clinical and Translational Science Institute, Boston, MA
     
Francisco J. Carrillo-Salinas
  • 5:30 PM - 5:45 PM (EDT)
    IND4 - Elucidating the Role of Host Purinergic Signaling During Rotavirus Infection
    Kristen A. Engevik1, John T. Gebert1, Jacob L. Perry1, Francesca J. Scribano1, Takahiro Kawagishi2, Harry Greenberg2, and Joseph M. Hyser1
    1Department of Molecular Virology & Microbiology, Baylor College of Medicine, Houston TX, 2Department of Medicine, Gastroenterology & Hepatology Stanford University, Stanford, CA
     
Kristen A. Engevik
  • 5:45 PM - 6:00 PM (EDT)
    IND5 - Klebsiella Pneumoniae in the Colonic Mucus Layer Influences Clostridioides Difficile Pathogenesis
    Taylor Ticer and Melinda A. Engevik
    Department of Regenerative Medicine, Medical University of South Carolina, Charleston, SC
Taylor Ticer

Wednesday, October 6, 2021

Tendai Hunyenyiwa, MS
SESSION 3 - Vascular Pathobiology
Session Co-Chairs: Tendai Hunyenyiwa, MS • Ramon Bossardi Ramos, PhD
12:30 PM - 3:00 PM (EDT)
Ramon Bossardi Ramos, PhD

12:30 PM -
1:15 PM (EDT)

Jay M. McDonald

Jay M. McDonald Memorial Keynote Lecture

“A Role for the Glycocalyx in Angiogenesis”

Patricia A. D'Amore, PhD, MBA • Schepens Eye Research Institute/Harvard Medical School

ABSTRACT
About the Keynote Speaker

Patricia A. D'Amore

Young Investigator Short Talks

  • 1:15 PM - 1:30 PM (EDT)
    VASC1 - Neuropilin-1 Regulates Vascular Smooth Muscle Cell Contractility and Blood Pressure
    Dakshnapriya Balasubbramanian1,2, George Lambrinos2,3, Vivian Cristofaro2,4, Alexander Bigger-Allen2,3, Beibei Wang1,2, Yao Gao1,2, Hong Chen1,2, Rosalyn M. Adam2,3, Maryrose P. Sullivan2,4, and Diane R. Bielenberg1,2
    1Vascular Biology Program, Boston Children’s Hospital, Boston, MA, 2Department of Surgery, Harvard Medical School, Boston, MA, 3Department of Urology Research, Boston Children’s Hospital, Boston, MA, 4Division of Urology, Veterans Affairs Boston Healthcare System, Boston, MA
     
Dakshnapriya Balasubbramanian
  • 1:30 PM - 1:45 PM (EDT)
    VASC2 - Loss of the Smooth-Muscle-Cell-Angiotensin II-Sensitive (SAS) lncRNA Triggers VSMC Hypertrophy and Cell Cycle Arrest: Application to Hypertension and Aortic Stiffness
    Cristina Espinosa-Diez, Mingjun Liu, Mingyuan Du, Sidney Mahan, and Delphine Gomez
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA
     
Cristina Espinosa-Diez
  • 1:45 PM - 2:00 PM (EDT)
    VASC3 - Specific Role of Endomucin in Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Internalization and Function
    Zhengping Hu1,2, Issahy Cano1,2, Magali Saint-Geniez1,2, Eric Ng1,2, and Patricia A. D’Amore1,2,3
    1Schepens Eye Research Institute of Massachusetts Eye and Ear, 2Departments of Ophthalmology and 3Pathology, Harvard Medical School, Boston, MA
     
Zhengping Hu
  • 2:00 PM - 2:15 PM (EDT)
    VASC4 - Obesity Inhibits Angiogenesis Through TWIST1-SLIT2 Signaling
    Tendai Hunyenyiwa, Kathryn Hendee, Kienna Matus, Priscilla Kyi, Tadanori Mammoto, and Akiko Mammoto
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI
     
Tendai Hunyenyiwa
  • 2:15 PM - 2:30 PM (EDT)
    VASC5 - COVID Coronary Vascular Thrombosis: Correlation with Neutrophil But Not Endothelial Activation
    Justin E. Johnson1, Dan Jane-wit1,2, Declan McGuone3, Mina L. Xu3, Richard N. Mitchell4, Peter Libby5, Jordan S. Pober1
    1Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 2Department of Cardiology, West Haven VA Medical Center, West Haven, CT, 3Department of Pathology, Yale University School of Medicine, New Haven, CT, 4Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 5Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
     
Justin E. Johnson
  • 2:30 PM - 2:45 PM (EDT)
    VASC6 - H3K4 Di-Methylation Governs Smooth Muscle Lineage Identity and Promotes Vascular Homeostasis by Restraining Plasticity
    Mingjun Liu 1,2, Cristina Espinosa-Diez 1, Sidney Mahan1, Mingyuan Du1,3, Anh T. Nguyen4, Scott Hahn1, Raja Chakraborty5,6, Adam C. Straub1,7,8, Kathleen A. Martin5,6, Gary K. Owens4,9, and Delphine Gomez1,2
    1Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, 2Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 3Department of Vascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, China, 4Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, 5Internal Medicine, Cardiovascular Medicine Section, Yale Cardiovascular Research Center, Yale University, New Haven, CT, 6Department of Pharmacology, Yale University, New Haven, CT, 7 Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 8Center for Microvascular Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, 9Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA
     
Mingjun Liu
  • 2:45 PM - 3:00 PM (EDT)
    VASC7 - SNAP29 Restricts Cardiac Arrhythmias by Insulating a Subset of Desmosomal Proteins and Connexin43 from Autophagic Degradation
    Jie Wang, Jason Pellman, Robert Lyon, Yan Liang, Valeria Mezzano, Jing Zhang, Vishal Nigam, Yusu Gu, Nancy Dalton, Kirk L. Peterson, and Farah Sheikh
    Department of Medicine, University of California - San Diego, San Diego, CA
     
Jie Wang
3:00 PM -
3:30 PM (EDT)
COFFEE BREAK
Nakisha Rutledge, BS
SESSION 4 - Inflammation and Immunopathology
Session Co-Chairs: Nakisha Rutledge, BS • Erik Butcher, PhD
3:30PM - 6:15 PM (EDT)
Erik Butcher, PhD

3:30 PM -
4:15 PM (EDT)

Janardan K. Reddy

Janardan K. Reddy Memorial Keynote Lecture

“How Inflammation Begets Pathology”

William A. Muller, MD, PhD • Northwestern University

ABSTRACT
About the Keynote Speaker

William A. Muller

Young Investigator Short Talks

  • 4:15 PM - 4:30 PM (EDT)
    INFL1 - Adipose Tissue Role in Neonatal Sepsis
    Michele J. Alves, Juliet Torres, Silvio Fernandes de Araujo Junior, Paollo Fadda, Jennifer Mele, Catherine Czeisler, and Jose Otero
    Department of Pathology, The Ohio State University, College of Medicine, Columbus, OH
     
Michele J. Alves
  • 4:30 PM - 4:45 PM (EDT)
    INFL2 - Differentially Methylated Positions After IL-6 in the Endothelium
    Ramon Bossardi Ramos, Nina Martino, and Alejandro Adam
    Department of Molecular and Cellular Physiology, Albany Medical College, Albany, NY
     
Ramon Bossardi Ramos
  • 4:45 PM - 5:00 PM (EDT)
    INFL8 - Interplay Between TNFα-Induced Inflammation and Metabolic Dysfunction in Retinal Pigment Epithelial Cells
    Daisy Y. Shu, Erik R. Butcher, Emmanuella Nnuji-John, Scott Frank, Rishi Shah, Siwei Cai, Deviprasad Gollapalli, and Magali Saint-Geniez
    Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA
Daisy Y. Shu
  • 5:00 PM - 5:15 PM (EDT)
    INFL4 - Identifying the Targets of Perforin Mediated Killing
    Vineet Garlapally, Vandana Chaturvedi, Kimberly Risma, and Michael Jordan
    Department of Pathobiology and Molecular Medicine, University of Cincinnati, Cincinnati Children’s Hospital, Cincinnati, OH
     
Vineet Garlapally
  • 5:15 PM - 5:30 PM (EDT)
    INFL5 - Cationic Antimicrobial Peptide, E35, Reduces LPS-induced Inflammation in Mice
    Joud Mulla1, Sultan Abdelhamid1, Zachary Secunda1, Bashar Al Matour1, Nijmeh Alsaadi1, Berthony Deslouches2, and Melanie J. Scott1
    1Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 2Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA
     
Joud Mulla
  • 5:30 PM - 5:45 PM (EDT)
    INFL6 - Perivascular Macrophages Prime Vascular Endothelial Cells to Promote Neutrophil Adhesion and Transendothelial Migration
    Xingsheng Ren, Jessica M. Urbanczyk, and Ronen Sumagin
    Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL
     
Xingsheng Ren
  • 5:45 PM - 6:00 PM (EDT)
    INFL7 - Human L2 Regulates Leukocyte Transmigration at a Unique Step between those Regulated by PECAM and CD99
    Nakisha S. Rutledge, David P. Sullivan, Faith Ogungbe, and William A. Muller
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL
     
Nakisha S. Rutledge
  • 6:00 PM - 6:15 PM (EDT)
    INFL3 - Identification and Characterization of a First Series of Small Molecule Inhibitors of Feline Islet Amyloid Polypeptide Aggregation
    Kelsey E. Duggan1, Kendra N. Nylen2, Nurhanis B.M. Isa2, Malikah O’Dell2, and Jessica S. Fortin1,3
    1College of Veterinary Medicine, Michigan State University, East Lansing, MI, 2Department of Chemistry, College of Natural Science, Michigan State University, East Lansing, MI, 3Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN
Kelsey E. Duggan

Thursday, October 7, 2021

Daisy Shu, PhD
SESSION 5 - Epithelial and Mucosal Pathobiology
Session Co-Chairs: Daisy Shu, PhD • Anny-Claude Luissint, PhD
12:30 PM - 2:30 PM (EDT)
Anny-Claude Luissint

12:30 PM -
1:15 PM (EDT)

Marilyn G. Farquhar

Marilyn G. Farquhar Memorial Keynote Lecture

“Plasticity of the Mucosal Barrier: Insights into Regulation of Epithelial Homeostasis and Repair”

Asma Nusrat, MD • University of Michigan

ABSTRACT
About the Keynote Speaker

Asma Nusrat

Young Investigator Short Talks

  • 1:15 PM - 1:30 PM (EDT)

    MUC1 - Giardia Duodenalis Alters Biochemical Properties of Intestinal Mucus During Infection
    Elena Fekete, Thibault Allain, and Andre G. Buret
    Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada

Elena Fekete
  • 1:30 PM - 1:45 PM (EDT)

    MUC2 - Characterizing the Mucin-Degrading Capacity of the Human Gut Microbiota
    Janiece Glover, Taylor Ticer, and Melinda A. Engevik
    Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC

Janiece Glover
  • 1:45 PM - 2:00 PM (EDT)

    MUC3 - Annickia Polycarpa Extract Attenuates DSS-Induced Colitis by Balancing Neutrophil Recruitment
    Nathaniel L. Lartey1, Hilda Vargas-Robles1, Idaira M. Guerrero-Fonseca1, Emmanuel K. Kumatia2, Augustine Ocloo3, and Michael Schnoor1
    1Department of Molecular Biomedicine, CINVESTAV-IPN, Mexico-City, Mexico, 2Department of Phytochemistry, Centre for Plant Medicine Research. Akuapem-Mampong, Ghana, 3Department of Biochemistry, Cell, and Molecular Biology, University of Ghana, Legon-Ghana

Nathaniel L. Lartey
  • 2:00 PM - 2:15 PM (EDT)

    MUC4 - Giardia Muris Infection Leads to Tuft Cell Hyperplasia at Later Stages of Infection
    Olivia Sosnowski, Thibault Allain, Elena Fekete, Derek M. McKay, and Andre G. Buret
    Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada

Olivia Sosnowski
  • 2:15 PM - 2:30 PM (EDT)

    MUC5 - Transcorneal Electric Stimulation Therapy Induce Dry Eye by [Ca2+]i Depletion of Goblet Cells and Reduce Mucin Production
    Menglu Yang1, Anton Lennikov1, Kinsang Cho1, Karen Chang1, Tor Paaske Utheim2, Darlene Dartt1, and Dong Feng Chen1
    1Schepens Eye Research Institute, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, 2Faculty of Medicine, University of Oslo, Oslo, Norway
     

Menglu Yang
2:30 PM -
3:00 PM (EDT)
COFFEE BREAK
Vik Meadows, MS
SESSION 6 - Liver Pathobiology
Session Co-Chairs: Vik Meadows, MS • Chhavi Goel, PhD
3:00 PM - 5:45 PM (EDT)
Chhavi Goel, PhD

3:00 PM -
3:45 PM (EDT)

Samuel W. French

Samuel W. French Memorial Keynote Lecture

“The Many Tiers of Liver Repair: Prometheus Needed Them All”

Satdarshan P. Monga, MD • University of Pittsburgh

ABSTRACT
About the Keynote Speaker

Satdarshan P. Monga

Young Investigator Short Talks

  • 3:45 PM - 4:00 PM (EDT)
    LIVER1 - TLR4 Deficiency Alters Platelet-Derived Exosome Release and Increases Mortality in a Model of Liver Regeneration
    Nijmeh Alsaadi1, Hamza Yazdani1, Matthew D. Neal1, and Roberto Ivan Mota Alvidrez1,2,3
    1Department of Surgery, 2McGowan Institute for Regenerative Medicine, 3Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA
     
Nijmeh Alsaadi
  • 4:00 PM - 4:15 PM (EDT)
    LIVER2 - β-catenin Conditional Knockout Elicits Protection Against Lithocholic Acid-Induced Cholestatic Injury in a Murine Model
    Chhavi Goel1, Rong Zhang1, Pamela Cornuet1, Xiaochao Ma2, and Kari Nejak-Bowen1,3
    1Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 2Center for Pharmacogenetics, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, 3Pittsburgh Liver Research Center, University of Pittsburgh School of Medicine, Pittsburgh, PA
     
Chhavi Goel
  • 4:15 PM - 4:30 PM (EDT)
    LIVER3 - Mitigation of High-Fat Diet-Induced Liver Injury in MS-NASH Mice: Modifications in Proteomic Signature
    Isabelle Harber, Dania Zeidan, Shannon McClintock, and Muhammad Nadeem Aslam
    Department of Pathology, University of Michigan, Ann Arbor, MI
     
Isabelle Harber
  • 4:30 PM - 4:45 PM (EDT)
    LIVER4 - PDGF Increases Hepatocyte-HMGB1 Synergistically with Stimulation of Heparan Sulfate in vitro and Alters Hepatocyte Exosome Release In TLR4 Deficient Mice
    Zeyu Liu1, Nijmeh Alsaadi1, Hamza Yazdani1, Matthew D. Neal1, and Roberto Ivan Mota Alvidrez1,2,3
    1Department of Surgery, 2McGowan Institute for Regenerative Medicine, 3Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA
     
Zeyu Liu
  • 4:45 PM - 5:00 PM (EDT)
    LIVER5 - Hepatic Autophagy Deficiency Leads to Exosome Overproduction and Pro-Inflammatory Response
    Gang Liu, Michelle Ma, and Xiao-Ming Yin
    Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA
     
Gang Liu
  • 5:00 PM - 5:15 PM (EDT)
    LIVER6 - Histamine Increases Hepatic and Intestinal Mast Cell Activation and Regulates Bile Acid Signaling During PSC
    Vik Meadows1, Debjyoti Kundu1, Vincent Zhou2, Lindsey Kennedy2, and Heather Francis2
    1Department of Biochemistry and Molecular Biology, 2Department of Medicine, Indiana University School of Medicine, Indianapolis, IN
     
Vik Meadows
  • 5:15 PM - 5:30 PM (EDT)
    LIVER7 - Durable Persistence of the Fetal Hepatocyte Phenotype After Liver Cell Transplantation
    Anders W. Ohman and Jennifer A. Sanders
    Department of Pathology and Laboratory Medicine, Brown University, Division of Pediatric Endocrinology, Rhode Island Hospital, Providence RI
     
Anders W. Ohman
  • 5:30 PM - 5:45 PM (EDT)
    LIVER8 - Transcriptional Correlation Analysis of Livers Undergoing Normothermic Machine Perfusion Links Gene Expression Patterns with Graft Functional Metrics
    John Santiago1, Siavash Raigani2, Anders Ohman1, Korkut Uygun3, Heidi Yeh3, and Jennifer A. Sanders1
    1Department of Pathology and Laboratory Medicine, Brown University, 2Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Transplant Surgery, Massachusetts General Hospital, Boston, MA
     
John Santiago

Awards Presentations
William B. Coleman, PhD, ASIP Executive Officer

Closing Remarks
Patricia D’Amore, PhD, ASIP President
Schepens Eye Research Institute/Harvard Medical School